Iqela lophando elidibeneyo elivela kwi-Harvard Medical School (HMS) kunye ne-MIT General Hospital ithi baphumelele ukulungiswa kwemveliso ye-microdisk laser usebenzisa indlela ye-PEC etching, okwenza umthombo omtsha we-nanophotonics kunye ne-biomedicine "ethembisayo."
(Imveliso ye-laser microdisk inokulungelelaniswa yi-PEC etching method)
Kwimihlaba yenanophotonicskunye ne-biomedicine, i-microdiskiilaserkunye ne-nanodisk lasers ziye zathembisaimithombo yokukhanyakunye ne-probes.Kwizicelo ezininzi ezinje nge-on-chip photonic communication, on-chip bioimaging, biochemical sensing, kunye nequantum photon information processing, kufuneka bafezekise imveliso yelaser ekumiseleni ubude be-wavelength kunye ne-ultra-narrow band echaneka.Nangona kunjalo, kuhlala kungumngeni ukwenza i-microdisk kunye ne-nanodisk lasers yolu bude buchanekileyo kwinqanaba elikhulu.Iinkqubo zangoku ze-nanofabrication zizisa i-randomness ye-diameter ye-disc, eyenza kube nzima ukufumana i-wavelength emiselweyo kwi-laser mass processing kunye nemveliso.Ngoku, iqela labaphandi abavela kwi-Harvard Medical School kunye ne-Massachusetts General Hospital's Wellman CentreUnyango lwe-Optoelectroniciye yavelisa i-optochemical (PEC) yobuchule bokuyila obunceda ukuchaneka ngokuchanekileyo i-laser wavelength ye-microdisk laser ngokuchaneka kwe-subnanometer.Umsebenzi upapashwa kwiphephancwadi i-Advanced Photonics.
I-Photochemical etching
Ngokweengxelo, indlela entsha yeqela yenza ukuba kwenziwe ii-laser ze-micro-disk kunye ne-nanodisk laser arrays ezinobude obuchanekileyo, obumiselwe kwangaphambili.Isitshixo kule mpumelelo kukusetyenziswa kwe-PEC etching, ebonelela ngendlela esebenzayo kunye neyonyukayo yokulungisa kakuhle ubude be-laser microdisc.Kwiziphumo ezingentla, iqela lifumene ngempumelelo i-indium Gallium arsenide phosphating microdisks ehlanganiswe ne-silica kwi-indium phosphide column structure.Emva koko balungisa ubude belaser yezi microdisks ngokuchanekileyo kwixabiso elimiselweyo ngokwenza i-photochemical etching kwisisombululo esixutywe se-sulfuric acid.
Baphinde baphande iindlela kunye ne-dynamics ye-photochemical etchings (PEC) etchings.Ekugqibeleni, badlulisele i-wavelength-tuned microdisk array kwi-polydimethylsiloxane substrate ukuvelisa amasuntswana e-laser azimeleyo, ahlukeneyo kunye namaza ahlukeneyo e-laser.I-microdisk enesiphumo ibonisa i-ultra-wideband bandwidth ye-laser emission, kunye nelaserkwikholomu engaphantsi kwe-0.6 nm kunye neqhekeza elizimeleyo elingaphantsi kwe-1.5 nm.
Ukuvula umnyango kwizicelo ze-biomedical
Esi siphumo sivula umnyango kwii-nanophotonics ezininzi ezintsha kunye nezicelo ze-biomedical.Ngokomzekelo, ii-laser ze-microdisk ezizimeleyo zinokusebenza njengeebhakhowudi ze-physico-optical kwiisampulu zebhayoloji ezingafaniyo, ezivumela ukuleyibhelilwa kweentlobo ezithile zeeseli kunye nokujoliswa kweemolekyuli ezithile kuhlalutyo oluphindaphindiweyo. njenge-organic fluorophores, amachaphaza e-quantum, kunye namaso e-fluorescent, anobubanzi obuphumayo bomgca.Ngoko ke, zimbalwa iindidi zeeseli ezinokuthi zibhalwe ngexesha elinye.Ngokwahlukileyo, i-ultra-narrow band light emission ye-microdisk laser iya kukwazi ukuchonga iintlobo ezininzi zeeseli ngaxeshanye.
Iqela livavanye kwaye labonisa ngempumelelo amasuntswana e-laser microdisk alungiswe ngokuchanekileyo njengee-biomarkers, ezisebenzisa ukulebhelisha iiseli ze-epithelial zebele eziqhelekileyo ze-MCF10A.Ngokukhutshwa kwazo kwe-ultra-wideband, ezi lasers zinokubanakho ukuguqula i-biosensing, zisebenzisa iindlela eziqinisekisiweyo zebhayomedical kunye ne-optical ezifana ne-cytodynamic imaging, flow cytometry, kunye nohlalutyo lwe-multi-omics.Itekhnoloji esekelwe kwi-PEC etching iphawula ukuqhubela phambili okukhulu kwiilaser ze-microdisk.I-scalability yendlela, kunye nokuchaneka kwayo kwe-subnanometer, ivula amathuba amatsha ezicelo ezingenakubalwa ze-laser kwi-nanophotonics kunye nezixhobo ze-biomedical, kunye neebhakhowudi zeeseli ezithile kunye neeamolekyuli zohlalutyo.
Ixesha lokuposa: Jan-29-2024