Iqela elihlangeneyo lophando elivela kwiHarvard Medical School (HMS) kunye neMIT General Hospital lithi likwazile ukulungisa imveliso ye-microdisk laser besebenzisa indlela ye-PEC etching, nto leyo eyenza umthombo omtsha we-nanophotonics kunye ne-biomedicine "uthembisayo."
(Imveliso ye-microdisk laser ingalungiswa ngendlela ye-PEC etching)
Kwimimandla yeii-nanophotonicskunye ne-biomedicine, i-microdiskiileyizakwaye ii-laser ze-nanodisk ziye zaba nethembaimithombo yokukhanyakunye neeprobes. Kwizicelo ezininzi ezifana nonxibelelwano lwe-photonic kwi-chip, i-bioimaging kwi-chip, i-biochemical sensing, kunye ne-quantum photon information processing, kufuneka zifezekise i-laser output ekumiseleni ubude be-wavelength kunye nokuchaneka kwebhendi enqamlezileyo. Nangona kunjalo, kusengumngeni ukuvelisa ii-microdisk kunye ne-nanodisk lasers zale wavelength ichanekileyo ngomlinganiselo omkhulu. Iinkqubo zangoku ze-nanofabrication zizisa ukungalingani kwe-disc diameter, okwenza kube nzima ukufumana ubude be-wavelength obumiselweyo ekucutshungulweni nasekuvelisweni kwe-laser mass. Ngoku, iqela labaphandi abavela kwiHarvard Medical School kunye neMassachusetts General Hospital's Wellman Center forAmayeza e-Optoelectroniciphuhlise indlela entsha yokukrola i-optochemical (PEC) enceda ekulungiseni ngokuchanekileyo ubude be-laser ye-microdisk laser ngokuchaneka kwe-subnanometer. Lo msebenzi upapashwe kwijenali i-Advanced Photonics.
Ukukrola nge-photochemical
Ngokweengxelo, indlela entsha yeqela ivumela ukwenziwa kwee-laser ze-micro-disk kunye nee-nanodisk laser arrays ezine-wavelengths ezichanekileyo nezimiselwe kwangaphambili. Isitshixo sale mpumelelo kukusetyenziswa kwe-PEC etching, ebonelela ngendlela esebenzayo neyonganyelwayo yokulungisa ubude be-wavelength ye-microdisc laser. Kwiziphumo ezingentla, iqela liphumelele ukufumana ii-indium Gallium arsenide phosphating microdisks ezigqunywe yi-silica kwisakhiwo sekholamu ye-indium phosphide. Emva koko balungisa ubude be-laser balezi microdisks ngokuchanekileyo kwixabiso elimiselweyo ngokwenza i-photochemical etching kwisisombululo esixutyiweyo se-sulfuric acid.
Baphande neendlela zokusebenza kunye ne-dynamics ye-photochemical etchings ethile (PEC). Ekugqibeleni, badlulisele i-microdisk array elungisiweyo ngobude kwi-polydimethylsiloxane substrate ukuze kuveliswe amasuntswana e-laser azimeleyo, ahlukeneyo ane-laser wavelengths ezahlukeneyo. I-microdisk ephumayo ibonisa i-bandwidth ye-ultra-wideband yokukhupha i-laser, kunyeilezakwikholam engaphantsi kwe-0.6 nm kunye nesuntswana elihlukanisiweyo elingaphantsi kwe-1.5 nm.
Ukuvula ucango lwezicelo ze-biomedical
Esi siphumo sivula ithuba lokufumana ii-nanophotonics ezininzi ezintsha kunye nezicelo ze-biomedical. Umzekelo, ii-laser ze-microdisk ezizimeleyo zingasebenza njengee-barcode ze-physico-optical zeesampulu zebhayoloji ezahlukeneyo, okuvumela ukulebhelwa kweentlobo ezithile zeeseli kunye nokujoliswa kweemolekyuli ezithile kuhlalutyo lwe-multiplex. Ukulebhelwa kohlobo oluthile lweeseli ngoku kwenziwa kusetyenziswa ii-biomarkers eziqhelekileyo, ezifana nee-organic fluorophores, ii-quantum dots, kunye nee-fluorescent beads, ezine-wide emission linewidths. Ke ngoko, zimbalwa iintlobo ezithile zeeseli ezinokulebhelwa ngaxeshanye. Ngokwahlukileyo koko, ukukhutshwa kokukhanya kwebhendi encinci kakhulu kwe-microdisk laser kuya kukwazi ukuchonga iintlobo ezininzi zeeseli ngaxeshanye.
Iqela livavanye kwaye labonisa ngempumelelo amasuntswana e-laser e-microdisk alungiswe ngokuchanekileyo njengee-biomarkers, liwasebenzisa ukulebhelisha iiseli ze-epithelial zesifuba eziqhelekileyo ezikhuliswe yi-MCF10A. Ngokukhupha kwazo i-ultra-wideband, ezi lasers zinokuguqula i-biosensing, zisebenzisa iindlela ezivunyiweyo ze-biomedical kunye ne-optical ezifana ne-cytodynamic imaging, i-flow cytometry, kunye nohlalutyo lwe-multi-omics. Itekhnoloji esekelwe kwi-PEC etching iphawula inkqubela phambili enkulu kwi-microdisk lasers. Ukwanda kwendlela, kunye nokuchaneka kwayo kwe-subnanometer, kuvula amathuba amatsha okusetyenziswa kwe-laser ezininzi kwi-nanophotonics kunye nezixhobo ze-biomedical, kunye neebhakhowudi zenani elithile leeseli kunye neemolekyuli zohlalutyo.
Ixesha leposi: Jan-29-2024