Imigaqo yokufota nge-photoacoustic

Imigaqo yokufota nge-photoacoustic

I-Photoacoustic Imaging (PAI) yindlela yokwenza imifanekiso yezonyango edibanisai-opticskunye ne-acoustics ukuvelisa imiqondiso ye-ultrasonic kusetyenziswa ukusebenzisana kweukukhanyangezicubu ukuze kufunyanwe imifanekiso yezicubu echanekileyo. Isetyenziswa kakhulu kwiinkalo zonyango lwebhayoloji, ingakumbi ekufumaneni ithumba, imifanekiso yemithambo yegazi, imifanekiso yesikhumba kunye nezinye iinkalo.

Umgaqo:
1. Ukufunxwa kokukhanya kunye nokwanda kobushushu: – I-Photoacoustic imaging isebenzisa isiphumo sobushushu esiveliswa kukufunxwa kokukhanya. Iimolekyuli zepigment kwizicubu (umz., i-hemoglobin, i-melanin) zifunxwa ii-photons (ngokuqhelekileyo ukukhanya okukufutshane ne-infrared), eziguqulwa zibe ngamandla obushushu, nto leyo ebangela ukuba amaqondo obushushu asekuhlaleni anyuke.
2. Ukwanda kobushushu kubangela i-ultrasound: – Ukunyuka kobushushu kukhokelela ekwandeni okuncinci kobushushu kwezicubu, okuvelisa amaza oxinzelelo (umz. i-ultrasound).
3. Ukufunyanwa kwe-Ultrasonic: – Amaza e-ultrasound avelisiweyo asasazeka ngaphakathi kwithishu, kwaye ezi zimpawu kamva zamkelwe kwaye zirekhodwe zii-sensors ze-ultrasonic (ezifana nee-ultrasonic probes).
4. Ukwakhiwa kwakhona komfanekiso: isignali ye-ultrasonic eqokelelweyo iyabalwa kwaye icutshungulwe ukuze kwakhiwe kwakhona isakhiwo kunye nomfanekiso womsebenzi wezicubu, nto leyo enokubonelela ngeempawu zokufunxa ezibonakalayo zezicubu. Iingenelo ze-photoacoustic imaging: Umahluko ophezulu: I-photoacoustic imaging ixhomekeke kwiimpawu zokufunxa ukukhanya kwezicubu, kwaye izicubu ezahlukeneyo (ezifana negazi, amafutha, izihlunu, njl.njl.) zinamandla ahlukeneyo okufunxa ukukhanya, ngoko ke inokubonelela ngemifanekiso engafaniyo. Isisombululo esiphezulu: Ukusebenzisa isisombululo esiphezulu sendawo ye-ultrasound, i-photoacoustic imaging inokufikelela kwi-millimeter okanye kwi-sub-millimeter imaging ngokuchanekileyo. Ayingenisi: I-photoacoustic imaging ayingenisi, ukukhanya kunye nesandi aziyi kubangela umonakalo kwizicubu, zifanelekile kakhulu ekuxilongweni kwabantu. Amandla okujonga ubunzulu: Xa kuthelekiswa ne-optical imaging yendabuko, i-photoacoustic imaging inokungena kwiisentimitha ezimbalwa phantsi kolusu, efanelekileyo kwi-deep tissue imaging.

Isicelo:
1. Umzobo wemithambo yegazi: – Umzobo we-photoacoustic unokubona iipropati ezifunxa ukukhanya ze-hemoglobin egazini, ukuze ukwazi ukubonisa ngokuchanekileyo ulwakhiwo kunye nemeko ye-oxygenation yemithambo yegazi ukuze kujongwe ukujikeleza kwegazi okuncinci kunye nokugweba izifo.
2. Ukufunyanwa kwethumba: – I-Angiogenesis kwizicubu zethumba idla ngokuba yinto eninzi kakhulu, kwaye imifanekiso ye-photoacoustic inokunceda ekubonweni kwangethuba kwethumba ngokufumanisa iingxaki kwisakhiwo semithambo yegazi.
3. Umzobo osebenzayo: – Umzobo we-photoacoustic unokuvavanya ukubonelelwa kweoksijini kwizicubu ngokufumanisa uxinano lwe-oxygenation kunye ne-deoxyhemoglobin kwizicubu, nto leyo ebaluleke kakhulu ekujongeni ukusebenza kwezifo ezifana nomhlaza kunye nesifo sentliziyo.
4. Umfanekiso wolusu: – Ngenxa yokuba umfanekiso we-photoacoustic ubuthathaka kakhulu kwizicubu ezingaphezulu, ufanelekile ekubonweni kwangethuba komhlaza wolusu kunye nohlalutyo lweengxaki zolusu.
5. Imifanekiso yobuchopho: Imifanekiso ye-photoacoustic inokufumana ulwazi lokuhamba kwegazi lobuchopho ngendlela engangenisi gazi ukuze kufundwe izifo zobuchopho ezifana nestroke kunye nesifo sokuwa.

Imingeni kunye neendlela zophuhliso lwemifanekiso ye-photoacoustic:
Umthombo wokukhanyaukhetho: Ukungena kokukhanya kwiiwavelengths ezahlukeneyo kwahlukile, indlela yokukhetha isisombululo esifanelekileyo sokulinganisela ubude bewavelength kunye nobunzulu bokungena ngumceli mngeni. Ukucubungula isignali: Ukufunyanwa kunye nokucubungula isignali ze-ultrasonic kufuna ii-algorithms ezikhawulezayo nezichanekileyo, kwaye uphuhliso lwetekhnoloji yokwakha kwakhona umfanekiso nalo lubalulekile. Ukuthatha imifanekiso ngeendlela ezininzi: Ukuthatha imifanekiso ye-photoacoustic kunokudityaniswa nezinye iindlela zokuthatha imifanekiso (ezifana ne-MRI, i-CT, i-ultrasound imaging) ukubonelela ngolwazi olupheleleyo lwe-biomedical.

I-Photoacoustic imaging yiteknoloji entsha neyimisebenzi emininzi ye-biomedical imaging, eneempawu zomahluko ophezulu, isisombululo esiphezulu kunye nokungangenisi. Ngophuhliso lwetekhnoloji, i-photoacoustic imaging ineethuba ezibanzi zokusetyenziswa ekuxilongweni kwezonyango, uphando olusisiseko lwebhayoloji, uphuhliso lwamayeza kunye nezinye iinkalo.