Imigaqo ye-photoacoustic imaging

Imigaqo ye-photoacoustic imaging

I-Photoacoustic Imaging (PAI) yindlela yokucinga yonyango edibanisaopticskunye ne-acoustics ukuvelisa imiqondiso ye-ultrasonic usebenzisa intsebenziswano yeukukhanyangethishu ukuze ufumane imifanekiso yethishu enesisombululo esiphezulu. Isetyenziswa ngokubanzi kwiinkalo ze-biomedical, ngakumbi ekubhaqweni kwe-tumor, i-vascular imaging, imaging yesikhumba kunye nezinye iinkalo.

Umgaqo:
1. Ukuxutywa kokukhanya kunye nokwandiswa kwe-thermal: - I-Photoacoustic imaging isebenzisa umphumo we-thermal oveliswa kukukhanya kokukhanya. Iimolekyuli ze-pigment ezikwithishu (umzekelo, i-hemoglobin, i-melanin) zifunxa iiphotons (ezidla ngokuba kufuphi ne-infrared light), eziguqulwa zibe ngamandla obushushu, nto leyo ebangela ukuba ubushushu bendawo bunyuke.
2. Ukwandiswa kwe-thermal kubangela i-ultrasound: - Ukunyuka kobushushu kukhokelela ekwandiseni okuncinci kwe-thermal ye-tissue, evelisa amaza oxinzelelo (okt ultrasound).
3. Ukufunyanwa kwe-Ultrasonic: – Amaza e-ultrasonic avelisiweyo asasaza ngaphakathi kwezicubu, kwaye ezi zibonakaliso emva koko zifunyenwe kwaye zirekhodwe ngeenzwa ze-ultrasonic (ezifana ne-ultrasonic probes).
4. Ukwakhiwa kwakhona komfanekiso: isibonakaliso se-ultrasonic esiqokelelweyo sibalwa kwaye sicutshungulwe ukuze kwakhiwe kwakhona isakhiwo kunye nomsebenzi womfanekiso we-tissue, enokubonelela ngeempawu ze-optical absorption of the tissue. Izinto eziluncedo kwimifanekiso yefotoacoustic: Ukwahluka okuphezulu: Ukucinga ngefotoacoustic kuxhomekeke kwiimpawu zokufunxa ukukhanya kwezicubu, kunye nezicubu ezahlukeneyo (ezifana negazi, amanqatha, izihlunu, njl.njl.) zinezakhono ezahlukeneyo zokufunxa ukukhanya, ngoko kunokubonelela ngemifanekiso ephezulu. Isisombululo esiphezulu: Ukusebenzisa isisombululo esiphezulu se-spatial ye-ultrasound, i-photoacoustic imaging inokufikelela kwi-millimeter okanye nakwi-millimeter yokuchaneka kwe-imaging. I-Non-invasive: I-Photoacoustic imaging ayinayo i-invasive, ukukhanya kunye nesandi akuyi kubangela umonakalo wezicubu, zifaneleke kakhulu ukuxilongwa kwezonyango lomntu. Ubunzulu besakhono sokucinga: Xa kuthelekiswa nemifanekiso yemveli ye-optical, imaging ye-photoacoustic inokungena kwiisentimitha ezininzi phantsi kwesikhumba, esilungele ukubonwa kwezicubu ezinzulu.

Isicelo:
1. I-Vascular imaging: - I-Photoacoustic imaging inokubona iimpawu zokukhanya kwe-hemoglobin egazini, ngoko inokubonisa ngokuchanekileyo isakhiwo kunye nesimo se-oxygen yemithambo yegazi ukubeka iliso kwi-microcirculation kunye nokugweba izifo.
2. Ukufumanisa i-tumor: - I-Angiogenesis kwizicubu ze-tumor ngokuqhelekileyo zininzi kakhulu, kwaye i-photoacoustic imaging inokunceda ukufunyanwa kwangoko kwamathumba ngokufumanisa ukungaqhelekanga kwisakhiwo se-vascular.
3. Ukucinga okusebenzayo: - I-Photoacoustic imaging inokuvavanya ukunikezelwa kwe-oksijini yezicubu ngokufumanisa ukuxinwa kwe-oxygenation kunye ne-deoxyhemoglobin kwii-tissue, ezibaluleke kakhulu ekubekweni iliso kokusebenza kwezifo ezifana nomhlaza kunye nesifo senhliziyo.
4. Imifanekiso yolusu: – Ngenxa yokuba ifotoacoustic imaging inovelwano kakhulu kwithishu engaphezulu, ifanelekile ukufunyaniswa kwangoko komhlaza wolusu kunye nokuhlalutya okungaqhelekanga kolusu.
5. Ukucinga ngengqondo: I-Photoacoustic imaging inokufumana ulwazi lokuhamba kwegazi kwi-cerebral ngendlela engabonakaliyo kwisifundo sezifo zengqondo ezifana ne-stroke kunye ne-epilepsy.

Imiceli mngeni kunye nophuhliso lwezalathiso zefotoacoustic imaging:
Umthombo wokukhanyaukhetho: Ukungena kokukhanya kwamaza ahlukeneyo ahlukeneyo, indlela yokukhetha isisombululo sokulinganisa i-wavelength efanelekileyo kunye nobunzulu bokungena ngumngeni. Ukusetyenzwa komqondiso: Ukufumana kunye nokulungiswa kweempawu ze-ultrasonic kufuna i-algorithms yesantya esiphezulu kunye nechanekileyo, kunye nophuhliso lobugcisa bokwakha umfanekiso kwakhona kubalulekile. I-Multimodal imaging: I-Photoacoustic imaging inokudibaniswa kunye nezinye iindlela zokucinga (ezifana ne-MRI, CT, imaging ultrasound) ukubonelela ngolwazi olubanzi lwe-biomedical.

I-Photoacoustic imaging yiteknoloji entsha kunye ne-multi-functional ye-biomedical imaging, eneempawu zokuchasana okuphezulu, isisombululo esiphezulu kunye ne-non-invasive. Ngophuhliso lwetekhnoloji, umfanekiso we-photoacoustic unamathuba abanzi okusebenza kuxilongo lwezonyango, uphando olusisiseko lwebhayoloji, uphuhliso lwamachiza kunye neminye imimandla.